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Binding Parameters of [(11)C]MPC-6827, a Microtubule-Imaging PET Radiopharmaceutical in Rodents
Impairment and/or destabilization of neuronal microtubules (MTs) resulting from hyper-phosphorylation of the tau proteins is implicated in many pathologies, including Alzheimer’s disease (AD), Parkinson’s disease and other neurological disorders. Increasing scientific evidence indicates that MT-stab...
Autores principales: | Bansode, Avinash H., Bhoopal, Bhuvanachandra, Gollapelli, Krishna Kumar, Damuka, Naresh, Krizan, Ivan, Miller, Mack, Craft, Suzanne, Mintz, Akiva, Solingapuram Sai, Kiran Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140836/ https://www.ncbi.nlm.nih.gov/pubmed/37111252 http://dx.doi.org/10.3390/ph16040495 |
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