An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice

Endogenous retroviruses (ERVs) account for 8% of our genome, and, although they are usually silent in healthy tissues, they become reactivated and expressed in pathological conditions such as cancer. Several studies support a functional role of ERVs in tumour development and progression, specificall...

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Detalles Bibliográficos
Autores principales: Daradoumis, Joana, Ragonnaud, Emeline, Skandorff, Isabella, Nielsen, Karen Nørgaard, Bermejo, Amaia Vergara, Andersson, Anne-Marie, Schroedel, Silke, Thirion, Christian, Neukirch, Lasse, Holst, Peter Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141008/
https://www.ncbi.nlm.nih.gov/pubmed/37112906
http://dx.doi.org/10.3390/v15040926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141008/
https://www.ncbi.nlm.nih.gov/pubmed/37112906
http://dx.doi.org/10.3390/v15040926

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