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Molecular Integrative Analysis of the Inhibitory Effects of Dipeptides on Amyloid β Peptide 1–42 Polymerization

The major pathological feature of Alzheimer’s disease (AD) is the aggregation of amyloid β peptide (Aβ) in the brain. Inhibition of Aβ(42) aggregation may prevent the advancement of AD. This study employed molecular dynamics, molecular docking, electron microscopy, circular dichroism, staining of ag...

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Detalles Bibliográficos
Autores principales: Yuan, Nan, Ye, Lianmeng, Sun, Yan, Wu, Hao, Xiao, Zhengpan, Fu, Wanmeng, Chen, Zuqian, Pei, Yechun, Min, Yi, Wang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141046/
https://www.ncbi.nlm.nih.gov/pubmed/37108834
http://dx.doi.org/10.3390/ijms24087673