Cargando…
Molecular Integrative Analysis of the Inhibitory Effects of Dipeptides on Amyloid β Peptide 1–42 Polymerization
The major pathological feature of Alzheimer’s disease (AD) is the aggregation of amyloid β peptide (Aβ) in the brain. Inhibition of Aβ(42) aggregation may prevent the advancement of AD. This study employed molecular dynamics, molecular docking, electron microscopy, circular dichroism, staining of ag...
Autores principales: | Yuan, Nan, Ye, Lianmeng, Sun, Yan, Wu, Hao, Xiao, Zhengpan, Fu, Wanmeng, Chen, Zuqian, Pei, Yechun, Min, Yi, Wang, Dayong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141046/ https://www.ncbi.nlm.nih.gov/pubmed/37108834 http://dx.doi.org/10.3390/ijms24087673 |
Ejemplares similares
-
A Molecular Integrative Study on the Inhibitory Effects of WRR and ERW on Amyloid β Peptide (1–42) Polymerization and Cell Toxicity
por: Wu, Zhongyun, et al.
Publicado: (2023) -
Sustained Stimulation of β(2)AR Inhibits Insulin Signaling in H9C2 Cardiomyoblast Cells Through the PKA-Dependent Signaling Pathway
por: Pei, Jinli, et al.
Publicado: (2020) -
Studies on HBcAg-rBlo t 5-21 Fusion Protein Vaccine That Alleviates Blomia tropicalis Airway Inflammation
por: Pei, Yechun, et al.
Publicado: (2022) -
Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation
por: Braun, Gabriel A., et al.
Publicado: (2022) -
RRY Inhibits Amyloid-β(1–42) Peptide Aggregation and Neurotoxicity
por: Sun, Xicui, et al.
Publicado: (2021)