Human Embryonic Stem-Cell-Derived Exosomes Repress NLRP3 Inflammasome to Alleviate Pyroptosis in Nucleus Pulposus Cells by Transmitting miR-302c

Recent studies have shown that the NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is extensively activated in the process of intervertebral disc degeneration (IVDD), leading to the pyroptosis of nucleus pulposus cells (NPCs) and the exacerbation of the pathological developmen...

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Detalles Bibliográficos
Autores principales: Yu, Yawen, Li, Wenting, Xian, Tinghui, Tu, Mei, Wu, Hao, Zhang, Jiaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141109/
https://www.ncbi.nlm.nih.gov/pubmed/37108824
http://dx.doi.org/10.3390/ijms24087664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141109/
https://www.ncbi.nlm.nih.gov/pubmed/37108824
http://dx.doi.org/10.3390/ijms24087664

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