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Stabilization of the Quadruplex-Forming G-Rich Sequences in the Rhinovirus Genome Inhibits Uncoating—Role of Na(+) and K(+)

Rhinoviruses (RVs) are the major cause of common cold, a respiratory disease that generally takes a mild course. However, occasionally, RV infection can lead to serious complications in patients debilitated by other ailments, e.g., asthma. Colds are a huge socioeconomic burden as neither vaccines no...

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Detalles Bibliográficos
Autores principales: Real-Hohn, Antonio, Groznica, Martin, Kontaxis, Georg, Zhu, Rong, Chaves, Otávio Augusto, Vazquez, Leonardo, Hinterdorfer, Peter, Kowalski, Heinrich, Blaas, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141139/
https://www.ncbi.nlm.nih.gov/pubmed/37112983
http://dx.doi.org/10.3390/v15041003