A Novel Aldisine Derivative Exhibits Potential Antitumor Effects by Targeting JAK/STAT3 Signaling

The JAK/STAT3 signaling pathway is aberrantly hyperactivated in many cancers, promoting cell proliferation, survival, invasiveness, and metastasis. Thus, inhibitors targeting JAK/STAT3 have enormous potential for cancer treatment. Herein, we modified aldisine derivatives by introducing the isothiour...

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Detalles Bibliográficos
Autores principales: Wang, Dong-Ping, Wu, Li-Hong, Li, Rui, He, Na, Zhang, Qian-Yue, Zhao, Chen-Yang, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141377/
https://www.ncbi.nlm.nih.gov/pubmed/37103357
http://dx.doi.org/10.3390/md21040218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141377/
https://www.ncbi.nlm.nih.gov/pubmed/37103357
http://dx.doi.org/10.3390/md21040218

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