Structure–Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017–Present)

The epidermal growth factor receptor (EGFR) plays a critical role in the tumorigenesis of various forms of cancer. Targeting the mutant forms of EGFR has been identified as an attractive therapeutic approach and led to the approval of three generations of inhibitors. The quinazoline core has emerged...

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Detalles Bibliográficos
Autores principales: Șandor, Alexandru, Ionuț, Ioana, Marc, Gabriel, Oniga, Ilioara, Eniu, Dan, Oniga, Ovidiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141396/
https://www.ncbi.nlm.nih.gov/pubmed/37111291
http://dx.doi.org/10.3390/ph16040534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141396/
https://www.ncbi.nlm.nih.gov/pubmed/37111291
http://dx.doi.org/10.3390/ph16040534

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