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Increased Clinical Signs and Mortality in IFNAR((−/−)) Mice Immunised with the Bluetongue Virus Outer-Capsid Proteins VP2 or VP5, after Challenge with an Attenuated Heterologous Serotype

Bluetongue is an economically important disease of domesticated and wild ruminants caused by bluetongue virus (BTV). There are at least 36 different serotypes of BTV (the identity of which is determined by its outer-capsid protein VP2), most of which are transmitted by Culicoides biting midges. IFNA...

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Detalles Bibliográficos
Autores principales: Attoui, Houssam, Mohd Jaafar, Fauziah, Monsion, Baptiste, Klonjkowski, Bernard, Reid, Elizabeth, Fay, Petra C., Saunders, Keith, Lomonossoff, George, Haig, David, Mertens, Peter P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141489/
https://www.ncbi.nlm.nih.gov/pubmed/37111488
http://dx.doi.org/10.3390/pathogens12040602