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Inhibition of spinal ferroptosis-like cell death alleviates hyperalgesia and spontaneous pain in a mouse model of bone cancer pain

Bone cancer pain (BCP) impairs patients’ quality of life. However, the underlying mechanisms are still unclear. This study investigated the role of spinal interneuron death using a pharmacological inhibitor of ferroptosis in a mouse model of BCP. Lewis lung carcinoma cells were inoculated into the f...

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Detalles Bibliográficos
Autores principales: Ding, Zhuofeng, Liang, Xiaoshen, Wang, Jian, Song, Zongbin, Guo, Qulian, Schäfer, Michael K.E., Huang, Changsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141498/
https://www.ncbi.nlm.nih.gov/pubmed/37084690
http://dx.doi.org/10.1016/j.redox.2023.102700