Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells

Controlling transgene expression through an externally administered inductor is envisioned as a potent strategy to improve safety and efficacy of gene therapy approaches. Generally, inducible ON systems require a chimeric transcription factor (transactivator) that becomes activated by an inductor, w...

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Detalles Bibliográficos
Autores principales: Tristán-Manzano, María, Maldonado-Pérez, Noelia, Justicia-Lirio, Pedro, Cortijo-Gutierréz, Marina, Tristán-Ramos, Pablo, Blanco-Benítez, Carlos, Pavlovic, Kristina, Aguilar-González, Araceli, Muñoz, Pilar, Molina-Estevez, Francisco J., Griesche, Valerie, Marchal, Juan Antonio, Heras, Sara R., Benabdellah, Karim, Martin, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141506/
https://www.ncbi.nlm.nih.gov/pubmed/37125150
http://dx.doi.org/10.1016/j.omtn.2023.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141506/
https://www.ncbi.nlm.nih.gov/pubmed/37125150
http://dx.doi.org/10.1016/j.omtn.2023.03.018

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