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Distinct effects of two hearing loss–associated mutations in the sarcomeric myosin MYH7b
For decades, sarcomeric myosin heavy chain proteins were assumed to be restricted to striated muscle where they function as molecular motors that contract muscle. However, MYH7b, an evolutionarily ancient member of this myosin family, has been detected in mammalian nonmuscle tissues, and mutations i...
Autores principales: | Lee, Lindsey A., Barrick, Samantha K., Buvoli, Ada E., Walklate, Jonathan, Stump, W. Tom, Geeves, Michael, Greenberg, Michael J., Leinwand, Leslie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141508/ https://www.ncbi.nlm.nih.gov/pubmed/36963494 http://dx.doi.org/10.1016/j.jbc.2023.104631 |
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