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TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

Autophagy plays a pivotal role in physiology and pathophysiology, including cancer. Mechanisms of autophagy dysregulation in cancer remain elusive. Loss of function of TRIM28, a multifunction protein, is seen in familial kidney malignancy, but the mechanism by which TRIM28 contributes to the etiolog...

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Detalles Bibliográficos
Autores principales: Song, Tanjing, Lv, Suli, Ma, Xianyun, Zhao, Xuefeng, Fan, Li, Zou, Qingli, Li, Neng, Yan, Yingying, Zhang, Wen, Sun, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141522/
https://www.ncbi.nlm.nih.gov/pubmed/36935008
http://dx.doi.org/10.1016/j.jbc.2023.104621