Visualizing Heterogeneous Protein Conformations with Multi-Tilt Nanoparticle-Aided Cryo-Electron Microscopy Sampling

[Image: see text] Obtaining the heterogeneous conformation of small proteins is important for understanding their biological role, but it is still challenging. Here, we developed a multi-tilt nanoparticle-aided cryo-electron microscopy sampling (MT-NACS) technique that enables the observation of het...

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Detalles Bibliográficos
Autores principales: Kim, Changin, Kim, Yeeun, Lee, Sang Jin, Yun, So Ri, Choi, Jungkweon, Kim, Seong Ok, Yang, Yongsoo, Ihee, Hyotcherl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141564/
https://www.ncbi.nlm.nih.gov/pubmed/37068052
http://dx.doi.org/10.1021/acs.nanolett.3c00313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141564/
https://www.ncbi.nlm.nih.gov/pubmed/37068052
http://dx.doi.org/10.1021/acs.nanolett.3c00313

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