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Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ

[Image: see text] 14-3-3 proteins are dimeric hubs that bind hundreds of phosphorylated “clients” to regulate their function. Installing stable, functional mimics of phosphorylated amino acids into proteins offers a powerful strategy to study 14-3-3 function in cellular-like environments, but a prev...

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Detalles Bibliográficos
Autores principales: Zhu, Phillip, Stanisheuski, Stanislau, Franklin, Rachel, Vogel, Amber, Vesely, Cat Hoang, Reardon, Patrick, Sluchanko, Nikolai N., Beckman, Joseph S., Karplus, P. Andrew, Mehl, Ryan A., Cooley, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141581/
https://www.ncbi.nlm.nih.gov/pubmed/37122473
http://dx.doi.org/10.1021/acscentsci.3c00191