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Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ
[Image: see text] 14-3-3 proteins are dimeric hubs that bind hundreds of phosphorylated “clients” to regulate their function. Installing stable, functional mimics of phosphorylated amino acids into proteins offers a powerful strategy to study 14-3-3 function in cellular-like environments, but a prev...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141581/ https://www.ncbi.nlm.nih.gov/pubmed/37122473 http://dx.doi.org/10.1021/acscentsci.3c00191 |