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Intradermal Immunization of Soluble Influenza HA Derived from a Lethal Virus Induces High Magnitude and Breadth of Antibody Responses and Provides Complete Protection In Vivo

Immunogens mimicking the native-like structure of surface-exposed viral antigens are considered promising vaccine candidates. Influenza viruses are important zoonotic respiratory viruses with high pandemic potential. Recombinant soluble hemagglutinin (HA) glycoprotein-based protein subunit vaccines...

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Detalles Bibliográficos
Autores principales: Raj, Sneha, Vishwakarma, Preeti, Saxena, Shikha, Kumar, Varun, Khatri, Ritika, Kumar, Amit, Singh, Mrityunjay, Mishra, Surbhi, Asthana, Shailendra, Ahmed, Shubbir, Samal, Sweety
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141624/
https://www.ncbi.nlm.nih.gov/pubmed/37112692
http://dx.doi.org/10.3390/vaccines11040780