Intimal Sarcoma with MDM2/CDK4 Amplification and p16 Overexpression: A Review of Histological Features in Primary Tumor and Xenograft, with Immunophenotype and Molecular Profiling

Intimal sarcomas (IS) are rare malignant mesenchymal tumors arising in large blood vessels of the systemic and pulmonary circulation and also in the heart. They are morphologically similar to other spindle cell, poorly differentiated sarcomas. The prognosis is poor and depends mainly on surgical opt...

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Detalles Bibliográficos
Autores principales: Giner, Francisco, Machado, Isidro, Rubio-Martínez, Luis Alberto, López-Guerrero, José Antonio, Claramunt-Alonso, Reyes, Navarro, Samuel, Ferrández, Antonio, Mayordomo-Aranda, Empar, Llombart-Bosch, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141691/
https://www.ncbi.nlm.nih.gov/pubmed/37108696
http://dx.doi.org/10.3390/ijms24087535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141691/
https://www.ncbi.nlm.nih.gov/pubmed/37108696
http://dx.doi.org/10.3390/ijms24087535

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