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Intimal Sarcoma with MDM2/CDK4 Amplification and p16 Overexpression: A Review of Histological Features in Primary Tumor and Xenograft, with Immunophenotype and Molecular Profiling
Intimal sarcomas (IS) are rare malignant mesenchymal tumors arising in large blood vessels of the systemic and pulmonary circulation and also in the heart. They are morphologically similar to other spindle cell, poorly differentiated sarcomas. The prognosis is poor and depends mainly on surgical opt...
Autores principales: | Giner, Francisco, Machado, Isidro, Rubio-Martínez, Luis Alberto, López-Guerrero, José Antonio, Claramunt-Alonso, Reyes, Navarro, Samuel, Ferrández, Antonio, Mayordomo-Aranda, Empar, Llombart-Bosch, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141691/ https://www.ncbi.nlm.nih.gov/pubmed/37108696 http://dx.doi.org/10.3390/ijms24087535 |
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