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Targeting SIRT1/FoxO3a/Nrf2 and PI3K/AKT Pathways with Rebamipide Attenuates Acetic Acid-Induced Colitis in Rats

Rebamipide is a quinolone derivative that has been commonly used for the treatment of gastric and duodenal ulcers. However, the molecular mechanisms of rebamipide against acetic acid-evoked colitis have not been adequately examined. Hence, the current study aimed to investigate the ameliorative effe...

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Detalles Bibliográficos
Autores principales: Abdel-Fattah, Maha M., Hassanein, Emad H. M., Sayed, Ahmed M., Alsufyani, Shuruq E., El-Sheikh, Azza A. K., Arab, Hany H., Mohamed, Wafaa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142103/
https://www.ncbi.nlm.nih.gov/pubmed/37111290
http://dx.doi.org/10.3390/ph16040533