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Are Voltage Sensors Really Embedded in Muscarinic Receptors?
Unexpectedly, the affinity of the seven-transmembrane muscarinic acetylcholine receptors for their agonists is modulated by membrane depolarization. Recent reports attribute this characteristic to an embedded charge movement in the muscarinic receptor, acting as a voltage sensor. However, this expla...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142193/ https://www.ncbi.nlm.nih.gov/pubmed/37108699 http://dx.doi.org/10.3390/ijms24087538 |