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Biomimetic Silica Particles with Self-Loading BMP-2 Knuckle Epitope Peptide and Its Delivery for Bone Regeneration

Biomimetic silica deposition is an in-situ immobilization method for bioactive molecules under biocompatible conditions. The osteoinductive P4 peptide derived from the knuckle epitope of bone morphogenetic protein (BMP), which binds to BMP receptor-II (BMPRII), has been newly found to contain silica...

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Detalles Bibliográficos
Autores principales: Ki, Mi-Ran, Nguyen, Thi Khoa My, Park, Tae-In, Park, Hae-Min, Pack, Seung Pil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142205/
https://www.ncbi.nlm.nih.gov/pubmed/37111547
http://dx.doi.org/10.3390/pharmaceutics15041061