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Marine-Derived Lead Fascaplysin: Pharmacological Activity, Total Synthesis, and Structural Modification

Fascaplysin is a planar structure pentacyclic alkaloid isolated from sponges, which can effectively induce the apoptosis of cancer cells. In addition, fascaplysin has diverse biological activities, such as antibacterial, anti-tumor, anti-plasmodium, etc. Unfortunately, the planar structure of fascap...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Wang, Siyuan, Li, Haonan, Hou, Yonglian, Cao, Hao, Hua, Huiming, Li, Dahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142289/
https://www.ncbi.nlm.nih.gov/pubmed/37103365
http://dx.doi.org/10.3390/md21040226