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Amorphization of Ethenzamide and Ethenzamide Cocrystals—A Case Study of Single and Binary Systems Forming Low-Melting Eutectic Phases Loaded on/in Silica Gel

The applicability of different solvent-free approaches leading to the amorphization of active pharmaceutical ingredients (APIs) was tested. Ethenzamide (ET), an analgesic and anti-inflammatory drug, and two ethenzamide cocrystals with glutaric acid (GLU) and ethyl malonic acid (EMA) as coformers wer...

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Detalles Bibliográficos
Autores principales: Trzeciak, Katarzyna, Wielgus, Ewelina, Kaźmierski, Sławomir, Pawlak, Tomasz, Potrzebowski, Marek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142476/
https://www.ncbi.nlm.nih.gov/pubmed/37111719
http://dx.doi.org/10.3390/pharmaceutics15041234