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Amorphization of Ethenzamide and Ethenzamide Cocrystals—A Case Study of Single and Binary Systems Forming Low-Melting Eutectic Phases Loaded on/in Silica Gel
The applicability of different solvent-free approaches leading to the amorphization of active pharmaceutical ingredients (APIs) was tested. Ethenzamide (ET), an analgesic and anti-inflammatory drug, and two ethenzamide cocrystals with glutaric acid (GLU) and ethyl malonic acid (EMA) as coformers wer...
Autores principales: | Trzeciak, Katarzyna, Wielgus, Ewelina, Kaźmierski, Sławomir, Pawlak, Tomasz, Potrzebowski, Marek J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142476/ https://www.ncbi.nlm.nih.gov/pubmed/37111719 http://dx.doi.org/10.3390/pharmaceutics15041234 |
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