Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction

BACKGROUND: AMBRA1 is an intrinsically disordered protein, working as a scaffold molecule to coordinate, by protein-protein interaction, many cellular processes, including autophagy, mitophagy, apoptosis and cell cycle progression. The zebrafish genome contains two ambra1 paralogous genes (a and b),...

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Detalles Bibliográficos
Autores principales: Fontana, Camilla Maria, Terrin, Francesca, Facchinello, Nicola, Meneghetti, Giacomo, Dinarello, Alberto, Gambarotto, Lisa, Zuccarotto, Annalisa, Caichiolo, Micol, Brocca, Ginevra, Verin, Ranieri, Nazio, Francesca, Carnevali, Oliana, Cecconi, Francesco, Bonaldo, Paolo, Dalla Valle, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142490/
https://www.ncbi.nlm.nih.gov/pubmed/37106439
http://dx.doi.org/10.1186/s40659-023-00430-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142490/
https://www.ncbi.nlm.nih.gov/pubmed/37106439
http://dx.doi.org/10.1186/s40659-023-00430-9

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