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Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction
BACKGROUND: AMBRA1 is an intrinsically disordered protein, working as a scaffold molecule to coordinate, by protein-protein interaction, many cellular processes, including autophagy, mitophagy, apoptosis and cell cycle progression. The zebrafish genome contains two ambra1 paralogous genes (a and b),...
Autores principales: | Fontana, Camilla Maria, Terrin, Francesca, Facchinello, Nicola, Meneghetti, Giacomo, Dinarello, Alberto, Gambarotto, Lisa, Zuccarotto, Annalisa, Caichiolo, Micol, Brocca, Ginevra, Verin, Ranieri, Nazio, Francesca, Carnevali, Oliana, Cecconi, Francesco, Bonaldo, Paolo, Dalla Valle, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142490/ https://www.ncbi.nlm.nih.gov/pubmed/37106439 http://dx.doi.org/10.1186/s40659-023-00430-9 |
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