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Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization
BACKGROUND: Tumors are complex tissues containing collections of phenotypically diverse malignant and nonmalignant cells. We know little of the mechanisms that govern heterogeneity of tumor cells nor of the role heterogeneity plays in overcoming stresses, such as adaptation to different microenviron...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142502/ https://www.ncbi.nlm.nih.gov/pubmed/37106386 http://dx.doi.org/10.1186/s12915-023-01593-3 |