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Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

BACKGROUND: Tumors are complex tissues containing collections of phenotypically diverse malignant and nonmalignant cells. We know little of the mechanisms that govern heterogeneity of tumor cells nor of the role heterogeneity plays in overcoming stresses, such as adaptation to different microenviron...

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Detalles Bibliográficos
Autores principales:	Rajan, Sanjana, Franz, Emily M., McAloney, Camille A., Vetter, Tatyana A., Cam, Maren, Gross, Amy C., Taslim, Cenny, Wang, Meng, Cannon, Matthew V., Oles, Alexander, Roberts, Ryan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142502/ https://www.ncbi.nlm.nih.gov/pubmed/37106386 http://dx.doi.org/10.1186/s12915-023-01593-3

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