Synthesis, Evaluation of Enzyme Inhibition and Redox Properties of Potential Dual COX-2 and 5-LOX Inhibitors

Various dual inhibitors of COX-2 and 5-LOX enzymes have been developed so far in order to obtain more effective and safer anti-inflammatory drugs. The aim of this study was to design and synthesize new dual COX-2 and 5-LOX inhibitors, and to evaluate their enzyme inhibition potential and redox prope...

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Detalles Bibliográficos
Autores principales: Bošković, Jelena, Dobričić, Vladimir, Mihajlović, Marija, Kotur-Stevuljević, Jelena, Čudina, Olivera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142505/
https://www.ncbi.nlm.nih.gov/pubmed/37111306
http://dx.doi.org/10.3390/ph16040549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142505/
https://www.ncbi.nlm.nih.gov/pubmed/37111306
http://dx.doi.org/10.3390/ph16040549

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