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New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties

This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal. For that purpose, two new 1:1 cocrystals, namely lidocaine:dl-menthol and lidocaine:d-menthol, were prepared. The menthol ra...

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Detalles Bibliográficos
Autores principales: Ma, Panpan, Toussaint, Balthazar, Roberti, Enrica Angela, Scornet, Noémie, Santos Silva, Axel, Castillo Henríquez, Luis, Cadasse, Monique, Négrier, Philippe, Massip, Stéphane, Dufat, Hanh, Hammad, Karim, Baraldi, Cecilia, Gamberini, Maria Cristina, Richard, Cyrille, Veesler, Stéphane, Espeau, Philippe, Lee, Tu, Corvis, Yohann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142540/
https://www.ncbi.nlm.nih.gov/pubmed/37111588
http://dx.doi.org/10.3390/pharmaceutics15041102