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In Silico and In Vivo Studies of a Tumor-Penetrating and Interfering Peptide with Antitumoral Effect on Xenograft Models of Breast Cancer

The combination of a tumor-penetrating peptide (TPP) with a peptide able to interfere with a given protein–protein interaction (IP) is a promising strategy with potential clinical application. Little is known about the impact of fusing a TPP with an IP, both in terms of internalization and functiona...

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Detalles Bibliográficos
Autores principales: Marin, Gustavo H., Murail, Samuel, Andrini, Laura, Garcia, Marcela, Loisel, Severine, Tuffery, Pierre, Rebollo, Angelita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142558/
https://www.ncbi.nlm.nih.gov/pubmed/37111665
http://dx.doi.org/10.3390/pharmaceutics15041180