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Differential Effects of Hypoxia versus Hyperoxia or Physoxia on Phenotype and Energy Metabolism in Human Chondrocytes from Osteoarthritic Compared to Macroscopically Normal Cartilage

Chondrocyte phenotype and energy metabolism are altered in osteoarthritis (OA). However, most studies characterising the change in human chondrocyte behaviour in OA have been conducted in supraphysiological oxygen concentrations. The purpose of this study was to compare phenotype and energy metaboli...

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Detalles Bibliográficos
Autores principales: Jain, Lekha, Bolam, Scott M., Monk, A. Paul, Munro, Jacob T., Chen, Even, Tamatea, Jade, Dalbeth, Nicola, Poulsen, Raewyn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142591/
https://www.ncbi.nlm.nih.gov/pubmed/37108698
http://dx.doi.org/10.3390/ijms24087532