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Drug Discovery Targeting Post-Translational Modifications in Response to DNA Damages Induced by Space Radiation

DNA damage in astronauts induced by cosmic radiation poses a major barrier to human space exploration. Cellular responses and repair of the most lethal DNA double-strand breaks (DSBs) are crucial for genomic integrity and cell survival. Post-translational modifications (PTMs), including phosphorylat...

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Detalles Bibliográficos
Autores principales: Xie, Dafei, Huang, Qi, Zhou, Pingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142602/
https://www.ncbi.nlm.nih.gov/pubmed/37108815
http://dx.doi.org/10.3390/ijms24087656