Evolution of Natural Product Scaffolds as Potential Proteasome Inhibitors in Developing Cancer Therapeutics

Homeostasis between protein synthesis and degradation is a critical biological function involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome pathway (UPP) is a large, multi-protease complex that degrades most intracellular proteins and accounts for about 80% of cellu...

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Detalles Bibliográficos
Autores principales: Mir, Reyaz Hassan, Mir, Prince Ahad, Uppal, Jasreen, Chawla, Apporva, Patel, Mitesh, Bardakci, Fevzi, Adnan, Mohd, Mohi-ud-din, Roohi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142660/
https://www.ncbi.nlm.nih.gov/pubmed/37110167
http://dx.doi.org/10.3390/metabo13040509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142660/
https://www.ncbi.nlm.nih.gov/pubmed/37110167
http://dx.doi.org/10.3390/metabo13040509

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