Suppressing Kaposi’s Sarcoma-Associated Herpesvirus Lytic Gene Expression and Replication by RNase P Ribozyme

Kaposi’s sarcoma, an AIDS-defining illness, is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV), an oncogenic virus. In this study, we engineered ribozymes derived from ribonuclease P (RNase P) catalytic RNA with targeting against the mRNA encoding KSHV immediate early replication and transc...

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Detalles Bibliográficos
Autores principales: Liu, Yujun, Chen, Yuan-Chuan, Yan, Bin, Liu, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142857/
https://www.ncbi.nlm.nih.gov/pubmed/37110852
http://dx.doi.org/10.3390/molecules28083619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142857/
https://www.ncbi.nlm.nih.gov/pubmed/37110852
http://dx.doi.org/10.3390/molecules28083619

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