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Suppressing Kaposi’s Sarcoma-Associated Herpesvirus Lytic Gene Expression and Replication by RNase P Ribozyme

Kaposi’s sarcoma, an AIDS-defining illness, is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV), an oncogenic virus. In this study, we engineered ribozymes derived from ribonuclease P (RNase P) catalytic RNA with targeting against the mRNA encoding KSHV immediate early replication and transc...

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Detalles Bibliográficos
Autores principales:	Liu, Yujun, Chen, Yuan-Chuan, Yan, Bin, Liu, Fenyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142857/ https://www.ncbi.nlm.nih.gov/pubmed/37110852 http://dx.doi.org/10.3390/molecules28083619

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