Synthesis, Antiproliferative Effect and In Silico LogP Prediction of BIM-23052 Analogs Containing Tyr Instead of Phe

(1) Background: Hydrophobicity (or lipophilicity) is a limiting factor in the ability of molecules to pass through cell membranes and to perform their function. The ability to efficiently access cytosol is especially important when a synthetic compound has the potential to become a drug substance. D...

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Detalles Bibliográficos
Autores principales: Danalev, Dancho, Iliev, Ivan, Dobrev, Stefan, Angelova, Silvia, Petrin, Stoiko, Dzimbova, Tatyana, Ivanova, Elena, Borisova, Dessislava, Naydenova, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142861/
https://www.ncbi.nlm.nih.gov/pubmed/37111609
http://dx.doi.org/10.3390/pharmaceutics15041123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142861/
https://www.ncbi.nlm.nih.gov/pubmed/37111609
http://dx.doi.org/10.3390/pharmaceutics15041123

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