Identification of BACE-1 Inhibitors against Alzheimer’s Disease through E-Pharmacophore-Based Virtual Screening and Molecular Dynamics Simulation Studies: An Insilco Approach

Alzheimer is a severe memory and cognitive impairment neurodegenerative disease that is the most common cause of dementia worldwide and characterized by the pathological accumulation of tau protein and amyloid-beta peptides. In this study, we have developed E-pharmacophore modeling to screen the eMo...

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Detalles Bibliográficos
Autor principal: Chidambaram, Kumarappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142975/
https://www.ncbi.nlm.nih.gov/pubmed/37109481
http://dx.doi.org/10.3390/life13040952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142975/
https://www.ncbi.nlm.nih.gov/pubmed/37109481
http://dx.doi.org/10.3390/life13040952

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