Innovative Metrics for Reporting and Comparing the Glycan Structural Profile in Biotherapeutics

Glycosylation is a critical quality attribute in biotherapeutics, impacting properties such as protein stability, solubility, clearance rate, efficacy, immunogenicity, and safety. Due to the heterogenic and complex nature of protein glycosylation, comprehensive characterization is demanding. Moreove...

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Detalles Bibliográficos
Autores principales: Mastrangeli, Renato, Satwekar, Abhijeet, Bierau, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143042/
https://www.ncbi.nlm.nih.gov/pubmed/37110538
http://dx.doi.org/10.3390/molecules28083304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143042/
https://www.ncbi.nlm.nih.gov/pubmed/37110538
http://dx.doi.org/10.3390/molecules28083304

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