Evaluation of a Cardiovascular Systems Model for Design and Analysis of Hemodynamic Safety Studies

Early prediction, quantification and translation of cardiovascular hemodynamic drug effects is essential in pre-clinical drug development. In this study, a novel hemodynamic cardiovascular systems (CVS) model was developed to support these goals. The model consisted of distinct system- and drug-spec...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Snelder, Nelleke, Guo, Tingjie, van der Graaf, Piet H., van Hasselt, Johan. G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143046/
https://www.ncbi.nlm.nih.gov/pubmed/37111660
http://dx.doi.org/10.3390/pharmaceutics15041175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143046/
https://www.ncbi.nlm.nih.gov/pubmed/37111660
http://dx.doi.org/10.3390/pharmaceutics15041175

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