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The Isolation and Structure Elucidation of Spirotetronate Lobophorins A, B, and H8 from Streptomyces sp. CB09030 and Their Biosynthetic Gene Cluster

Lobophorins (LOBs) are a growing family of spirotetronate natural products with significant cytotoxicity, anti-inflammatory, and antibacterial activities. Herein, we report the transwell-based discovery of Streptomyces sp. CB09030 from a panel of 16 in-house Streptomyces strains, which has significa...

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Detalles Bibliográficos
Autores principales: Shi, Jie, Peng, Dian, Peng, Fei-Fei, Zhang, Qing-Bo, Duan, Yan-Wen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143065/
https://www.ncbi.nlm.nih.gov/pubmed/37110828
http://dx.doi.org/10.3390/molecules28083597