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Potent NTD-Targeting Neutralizing Antibodies against SARS-CoV-2 Selected from a Synthetic Immune System

The majority of neutralizing antibodies (NAbs) against SARS-CoV-2 recognize the receptor-binding domain (RBD) of the spike (S) protein. As an escaping strategy, the RBD of the virus is highly variable, evolving mutations to thwart a natural immune response or vaccination. Targeting non-RBD regions o...

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Detalles Bibliográficos
Autores principales: Li, Wenping, Wang, Fulian, Li, Yu, Yan, Lei, Liu, Lili, Zhu, Wei, Ma, Peixiang, Shi, Xiaojie, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143083/
https://www.ncbi.nlm.nih.gov/pubmed/37112683
http://dx.doi.org/10.3390/vaccines11040771