CYP2C19 Contributes to THP-1-Cell-Derived M2 Macrophage Polarization by Producing 11,12- and 14,15-Epoxyeicosatrienoic Acid, Agonists of the PPARγ Receptor

Although the functional roles of M1 and M2 macrophages in the immune response and drug resistance are important, the expression and role of cytochrome P450s (CYPs) in these cells remain largely unknown. Differential expression of the 12 most common CYPs (CYP1A1, 1A2, 1B1, 2B6, 2C8, 2C9, 2C19, 2D6, 2...

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Detalles Bibliográficos
Autores principales: Cho, Hee Young, Ahn, Sangzin, Cho, Yong-Soon, Seo, Su-Kil, Kim, Dong Hyun, Shin, Jae-Gook, Lee, Su-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143178/
https://www.ncbi.nlm.nih.gov/pubmed/37111350
http://dx.doi.org/10.3390/ph16040593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143178/
https://www.ncbi.nlm.nih.gov/pubmed/37111350
http://dx.doi.org/10.3390/ph16040593

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