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Synthesis of the Most Potent Isomer of μ-Conotoxin KIIIA Using Different Strategies

In the chemical synthesis of conotoxins with multiple disulfide bonds, the oxidative folding process can result in diverse disulfide bond connectivities, which presents a challenge for determining the natural disulfide bond connectivities and leads to significant structural differences in the synthe...

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Detalles Bibliográficos
Autores principales: Jian, Xunxun, Wu, Yong, Mei, Zaoli, Zhu, Xiaopeng, Zhangsun, Dongting, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143212/
https://www.ncbi.nlm.nih.gov/pubmed/37110612
http://dx.doi.org/10.3390/molecules28083377