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Novel Vulgarin Derivatives: Chemical Transformation, In Silico and In Vitro Studies

Vulgarin, an eudesmanolide sesquiterpene isolated from Artemisia judaica, was refluxed with iodine to produce two derivatives (1 and 2), which were purified and spectroscopically identified as naproxen methyl ester analogs. The reaction mechanism by which 1 and 2 were formed is explained using a sig...

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Detalles Bibliográficos
Autores principales: Sary, Hanan G., Khedr, Mohammed A., Orabi, Khaled Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143240/
https://www.ncbi.nlm.nih.gov/pubmed/37110654
http://dx.doi.org/10.3390/molecules28083421