Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes: Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype

The pentameric γ-Aminobutyric acid type A receptors (GABA(A)Rs) are ligand-gated ion channels that mediate the majority of inhibitory neurotransmission in the brain. In the cerebellum, the two main receptor subtypes are the 2α1/2β/γ and 2α6/2β/δ subunits. In the present study, an interaction proteom...

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Detalles Bibliográficos
Autores principales: Chen, Miao, Koopmans, Frank, Paliukhovich, Iryna, van der Spek, Sophie J. F., Dong, Jian, Smit, August B., Li, Ka Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143440/
https://www.ncbi.nlm.nih.gov/pubmed/37108794
http://dx.doi.org/10.3390/ijms24087632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143440/
https://www.ncbi.nlm.nih.gov/pubmed/37108794
http://dx.doi.org/10.3390/ijms24087632

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