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Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy

A series of 1,4-naphthoquinone derivatives containing were synthesized as anti-cancer agents and the crystal structure of compound 5a was confirmed by X-ray diffraction. In addition, the inhibitory activities against four cancer cell lines (HepG2, A549, K562, and PC-3) were tested, respectively, and...

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Detalles Bibliográficos
Autores principales: Tan, Hua-Yuan, Liang, Feng-Ming, Zhang, Wen-Jing, Zhang, Yi, Cui, Jun-Hao, Dai, Yu-Yu, Qiu, Xue-Mei, Wang, Wen-Hang, Zhou, Yue, Chen, Dan-Ping, Li, Cheng-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143525/
https://www.ncbi.nlm.nih.gov/pubmed/37110525
http://dx.doi.org/10.3390/molecules28083289