Marine Polyether Phycotoxin Palytoxin Induces Apoptotic Cell Death via Mcl-1 and Bcl-2 Downregulation

Palytoxin is considered one of the most potent biotoxins. As palytoxin-induced cancer cell death mechanisms remain to be elucidated, we investigated this effect on various leukemia and solid tumor cell lines at low picomolar concentrations. As palytoxin did not affect the viability of peripheral blo...

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Detalles Bibliográficos
Autores principales: Kim, Jaemyun, Ji, Seungwon, Lee, Jin-Young, Lorquin, Jean, Orlikova-Boyer, Barbora, Cerella, Claudia, Mazumder, Aloran, Muller, Florian, Dicato, Mario, Detournay, Olivier, Diederich, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143546/
https://www.ncbi.nlm.nih.gov/pubmed/37103372
http://dx.doi.org/10.3390/md21040233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143546/
https://www.ncbi.nlm.nih.gov/pubmed/37103372
http://dx.doi.org/10.3390/md21040233

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