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Marine Polyether Phycotoxin Palytoxin Induces Apoptotic Cell Death via Mcl-1 and Bcl-2 Downregulation
Palytoxin is considered one of the most potent biotoxins. As palytoxin-induced cancer cell death mechanisms remain to be elucidated, we investigated this effect on various leukemia and solid tumor cell lines at low picomolar concentrations. As palytoxin did not affect the viability of peripheral blo...
Autores principales: | Kim, Jaemyun, Ji, Seungwon, Lee, Jin-Young, Lorquin, Jean, Orlikova-Boyer, Barbora, Cerella, Claudia, Mazumder, Aloran, Muller, Florian, Dicato, Mario, Detournay, Olivier, Diederich, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143546/ https://www.ncbi.nlm.nih.gov/pubmed/37103372 http://dx.doi.org/10.3390/md21040233 |
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